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| Product Name: | Kojic Acid | MF: | C6H6O4 |
|---|---|---|---|
| EINECS No: | 142.11 | Melt Point: | 152-156 |
| Grade: | Cosmetic Raw Materials | Storage: | Cool Dry Place |
| Test Method: | UV | Sample: | Available |
| High Light: | White Crystal Kojic Dipalmitate Powder,Kojic Dipalmitate Powder 99% |
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Cosmetic Raw Material Kojic Acid Powder 99%
Kojic acid is kind of tyrosinase inhibitor by fermentation. It is odorless, colorless and safe. Many fermentative foods, such as soybean, soy sauce and wine, contain kojic acid. It also can be found in some microorganisms, including aspergillus oryzae, aspergillus parasiticus, aspergillus flavus, etc. Japan started to produce kojic acid in the 1970s.
Kojic acid is a kind of specialized inhibitor for melanin. It can prevent the tyrosinase activity through synthesizing with copper ion in the cells after it enters skin cells. Kojic acid and its derivative has better inhibitory effect on tyrosinase than any other skin whitening agents.
| tem | Specification |
| Appearance | White or off white crystal |
| Purity(%) | 99.0 min |
| Melt Point(℃) | 152-156 |
| Loss on Drying(%) | 0.5 max |
| Residueon Ignition(%) | 0.1 max |
| Heavy Metals(ppm) | 3 max |
| Iron(ppm) | 10 max |
| Arsenic(ppm) | 1 max |
| Chloride(ppm) | 100 max |
Application
1.in cosmetic field: It is used for macula-removing and whitening.In the human skin, tyrosine is oxidized and polymerized with oxygen-derived free radicals under the catalytic action of tyrosinase and then synthesized to melanin. Kojic acid can inhibit tyrosinase synthesis, so it can greatly inhibit the skin melanin formation; furthermore, kojic acid is safe and nontoxic and won’t cause white spot syndrome. Therefore, it has been widely added in the lotion, face mask, liquid cream and skin cream. Whitening cosmetics containing kojic acid are able to treat effectively the freckle, senile plaque.
2.Moreover, kojic acid is the mateial for making maltol and cthyl maltol.
3.In medicine field: kojic acid has no mutagenic action to eukaryotic cells. It is able to eliminate the free radicals in the human body, strengthen the activity of the leucocyte, so it is good for human health. Now kojic acid has been used as the an important material of cephalosporin-type antibiotics. The finished products have ideal effect in easing pain, relieving inflammation and curing many diseases.
4.In agriculture field: Kojic acid is used in producing biological pesticides. This kind of crop production promoter has significant effect on increasing production of grains and vegetables, no matter it is used as low-concentration foliage fertilizer for spraying or yield-increasing agent for root applying.
5.In other fields: kojic acid is also used as iron analytical reagent and film spotting agent.
Function
1.Kojic acid specialized inhibitor for melanin. It can prevent the tyrosinase activity through synthesizing with copper ion in the cells after it enters skin cells. Kojic acid and its derivative has better inhibitory effect on tyrosinase than any other skin whitening agents.It is assigned into various kinds of cosmetics for curing freckles,spots on the skin of old man,pigmentation and acne.
2.Can also eliminate free radical, strengthen cell activity of cell and keep the food fresh.
3.It has antibacterial and antifungal properties.
| Kojic acid Basic information | |
| Product Name | Kojic acid |
| Synonyms | 4H-Pyran-4-one, 5-hydroxy-2-(hydroxymethyl)-; 4H-Pyran-4-one,5-hydroxy-2-(hydroxymethyl)-; 5-hydroxy-2-(hydroxymethyl)-4h-pyran-4-on;kojic; Pyran-4-one, 5-hydroxy-2-(hydroxymethyl);2-HYDROXYMETHYL-5-HYDROXY-4-PYRONE; 5-Hydroxy-2-(hydroxymethyl)-γ-pyrone; Kojic acid |
| CAS | 501-30-4 |
| MF | C6H6O4 |
| MW | 142.11 |
| EINECS | 207-922-4 |
| Mol File | 501-30-4.mol |
| Kojic acid Chemical Properties | |
| Melting point | 152-155 °C (lit.) |
| Boiling point | 179.65°C (rough estimate) |
| density | 1.1712 (rough estimate) |
| refractive index | 1.4434 (estimate) |
| storage temp. | Store below +30°C. |
| pka | 7.9(at 25℃) |
| form | Crystalline Powder |
| color | White to beige-brown |
| Water Solubility | SOLUBLE |
| λmax | 269nm(CHCl3)(lit.) |
| Merck | 145,317 |
| BRN | 120895 |
| Stability: | Stable. Combustible. Incompatible with strong oxidizing agents. |
| CAS DataBase Reference | 501-30-4(CAS DataBase Reference) |
| NIST Chemistry Reference | 5-Hydroxy-2-(hydroxymethyl)-4h-pyran-4-one(501-30-4) |
| IARC | 3 (Vol. 79) 2001 |
| EPA Substance Registry System | Kojic acid (501-30-4) |
| Safety Information | |
| Hazard Codes | Xn |
| Risk Statements | 40-68 |
| Safety Statements | 22-24/25-36/37-36 |
| WGK Germany | 3 |
| RTECS | UQ0875000 |
| HS Code | 29329995 |
| Hazardous Substances Data | 501-30-4(Hazardous Substances Data) |
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