Food additives 20000fu Natto Extract Nattokinase Powder

Food additives 20000fu Natto Extract Nattokinase Powder

Nattokinase is a second-generation thrombolytic agent and one of the fibrinolytic enzymes. Nattokinase is a serine protease produced by Bscillus natto or Bacillus subtilis natto during the fermentation of natto, and it can be secreted outside the cell. Nattokinase has a strong fibrinolytic activity. It can not only directly act on fibrin, but also activate plasminogen in the body, thereby increasing the amount and effect of endogenous plasmin, thus showing a strong lytic activity. Thrombosis.

Nattokinase is a single-chain polypeptide consisting of 275 amino acid residues. The amino acid sequence contains 8 lysine residues and no cysteine residues. It has extremely high homology with other subtilisins, 86% homology with Bacillus subtilis BPN, and 70% and 72% homology with subtilisin DY and subtilisin Carlsberg, respectively. The theoretical molecular weight is 27728 Da. In the actual measurement, the measured molecular weight results are different due to different methods. The purified nattokinase is a white powder with no odor.

Function&Application:

Dissolve thrombus

Nattokinase can directly decompose thrombus, and the thrombolytic effect of wet natto per gram is equivalent to 1600IU of urokinase. Urokinase can only be injected, nattokinase can be injected or taken, and it can play a role in capillaries.

Prevent osteoporosis

Natto contains soy isoflavones and vitamin K2. Soy isoflavones can prevent the dissolution of calcium in bones, while vitamin K2 can fix calcium in bones. The combination of soy isoflavones and vitamin K2 can work tog to strengthen bones.

Antibacterial effect

Natto bacteria can also inhibit the pathogenic Escherichia coli 0-11 and 0144 of the same kind of 0-157 and other pathogenic bacteria such as Staphylococcus aureus, Salmonella, Listeria, etc. The antibacterial mechanism is that Natto bacteria can produce dipicolinic acid, a bactericidal substance.

Regulate the intestines and stomach, moisten the intestines and laxatives, detoxify and beautify the skin

The dipicolinic acid produced by Natto bacteria effectively kills and inhibits harmful bacteria and viruses in the intestinal tract. Make the intestinal flora achieve a healthy dynamic balance, quickly solve the problems of constipation, enteritis, and diarrhea, and restore a healthy intestine.

Significantly improve female menopausal syndrome

Women's menopausal symptoms and postmenopausal women's prone to osteoporosis are mainly caused by the decline of estrogen levels in the body. Soy flavonoids can supplement the lack of estrogen in the body, not only can significantly improve the symptoms of menopause, but also can prevent osteoporosis in women. Considering the effects of natto in detoxification, beauty and weight loss, natto is a very important health food for women.

Slow weight loss intuitively reduces postprandial blood sugar

Natto bacteria can persist in the intestines for about 1 week and can promote the proliferation of other beneficial bacteria. The nutrients absorbed by the human body become the bait of the bacteria in the intestines and are swallowed. In addition, nattokinase can burn fat, which makes it possible to lose weight. There is also natto sticky substance that plays the role of soaking and wrapping. Therefore, natto weight loss is slow and effective and will not rebound.

However, it is very intuitive that the blood glucose level after a meal has a clear downward trend. One is the role of natto bacteria in phagocytosis of glucose and mucus, and the other is the high elastase (or trypeptidase E, Elastase) in natto, which inhibits the increase in blood sugar. It has the effect of this enzyme contained in porcine pancreas, and the elastase of porcine pancreas has been used in the treatment of hyperglycemia.

Hangover, protect liver

After nattoase enters the human body, it builds an alcohol protective barrier through triple channels to promote hangover. In addition, a variety of active substances in natto activate liver cells, promote liver cell regeneration, improve liver function, protect the liver, and effectively prevent and improve fatty liver.

Prevent high blood pressure

Natto bacteria food contains angiotensin converting enzyme (ACE) inhibitor, which prevents angiotensin from becoming active form. The current research hotspot on the efficacy of nattokinase is thrombolysis.